DP Exosome

Dermal Papilla Derived Exosome

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A specialized exosome to reawaken Hair Follicle Stem Cells

DP Exosome represents a cutting-edge innovation in hair
restoration, harnessing the regenerative power of exosomes derived from 3D-cultured human dermal papilla spheroids. These nanoscale biological messengers are rich in growth factors, miRNAs, and proteins, delivering a potent signal directly to hair follicles to reactivate growth, reverse follicular
dysfunction, and combat multiple forms of hair loss.
Unlike conventional approaches, this therapy is specifically designed to reawaken dormant follicles, enhance follicular survival, and optimize the scalp environment, making it an ideal treatment for addressing androgenic alopecia, alopecia areata, chemotherapy-induced hair loss, and telogen effluvium.

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How it Works

Hair follicle stem cells (HFSCs) undergo cycles of dormancy and activation to power hair growth. In alopecia related to age, stress, hormones, and chemotherapy, hair follicle stem cells can become "stuck" in the dormant phase and unable to trigger hair growth. However, these stem cells are still present and viable. in the follicles. Our exosome activates dormant hair follicle stem cells, restoring the regenerative capacity of the follicle and triggering new hair growth.

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Sequences of Hair Growth via Dermal Papilla and Hair Follicle Stem Cells

 

The stages of differentiation of dermal follicle stem cells (HFSCs) into hair are:

•Activation: The dermal papilla (DP) releases a signal that activates the hair the HFSCs

•Proliferation and differentiation: The activated HFSCs proliferate and differentiate, forming the outer root sheath (ORS) and matrix. •Formation of the inner root sheath and hair shaft: The matrix forms the inner root sheath and hair shaft The hair growth cycle is a continuous process that consists of four phases:

•Anagen: The growth phase, when a new hair shaft is grown •Catagen: The regression phase

•Telogen: The resting phase

•Exogen: The shedding phase

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